Neúčinnosť vakcíny BCG (proti TBC) bola dokázaná pred tridsiatimi rokmi v rozsiahlej štúdii. Vo Švédsku je očkovanie BCG vakcínou od roku 1985 zakázané. Od roku 1995 v USA vakcínu BCG odporúčajú len rizikovým novorodencom (takým, ktoré sú trvalo vystavené chorým na TBC). V roku 1998 v Nemecku očkovanie proti TBC bolo odstránené zo zoznamu odporúčaných očkovaní.
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